Massive hemothorax following administration of intrapleural streptokinase
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چکیده
منابع مشابه
Acute hypoxemic respiratory failure following intrapleural thrombolytic therapy for hemothorax.
Intrapleural instillation of thrombolytic agents has been useful in the treatment of hemothorax when thoracostomy tube drainage is unsuccessful. We present a patient who developed acute hypoxemic respiratory failure following the intrapleural instillation of both streptokinase and urokinase 24 h apart. Hypoxemia most likely resulted from a direct effect of the products of fibrinolysis on the pu...
متن کاملThe systemic fibrinolytic activity of intrapleural streptokinase.
Intrapleural fibrinolytics probably improve the drainage of loculated pleural effusions and empyemas. Studies of crude indices of systemic coagulation suggest this effect is accompanied by little systemic fibrinolysis, but few studies have assessed this in detail. This study examines the systemic fibrinolytic activity of two intrapleural streptokinase (IPSK) regimes in detail. Eight patients re...
متن کاملIntrapleural streptokinase in the management of empyema.
BACKGROUND Significant morbidity and mortality result from the ineffective evacuation of empyema. Failure of conventional first line treatment with closed intercostal tube drainage and antibiotic therapy may result in fibrin deposition and loculated empyema. Enzymatic debridement using intrapleural instillation of streptokinase is a non-invasive therapeutic option which may obviate the need for...
متن کاملIntrapleural streptokinase for the treatment of chylothorax.
Chylothorax is suspected when milky white turbid fluid is obtained from thoracocentesis. Conservative management usually involves intercostal tube drainage, dietary restriction, and total parenteral nutrition. Surgery is indicated when conservative management fails. We describe a young woman with idiopathic chylothorax who failed conservative therapy but refused surgery. We instilled intrapleu...
متن کاملIntrapleural r-tPA in association with low-molecular heparin may cause massive hemothorax resulting in hypovolemia.
The use of intrapleural instillation of recombinant tissue plasminogen activator (r-tPA) in the treatment of pleural infection may increase pleural fluid drainage associated with a clinical and imaging improvement, leading to a faster resolution. The use of r-tPA is generally well tolerated. Here we report 2 cases of massive pleural hemorrhage resulting in life-threatening hypovolemia, in 2 pat...
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ژورنال
عنوان ژورنال: Annals of Thoracic Medicine
سال: 2011
ISSN: 1817-1737
DOI: 10.4103/1817-1737.82451